Frequently Asked Questions

The primary difference is duration of action. Tadalafil can last up to 36 hours, while Sildenafil typically lasts 4-6 hours. Tadalafil also has minimal food interactions, whereas Sildenafil should not be taken with high-fat meals. Additionally, Tadalafil offers both daily and as-needed dosing options, while Sildenafil is typically used as-needed only.

Both medications are PDE5 inhibitors. They work by blocking the enzyme phosphodiesterase type 5, which allows increased blood flow to the penis during sexual stimulation. This helps achieve and maintain an erection. Important: They only work when you are sexually aroused - they don't cause automatic erections.

Yes, generic versions of both medications are available. Generic Sildenafil has been available since 2017, and generic Tadalafil became available in 2018. Generic versions contain the same active ingredients and are FDA-approved as equivalent to brand-name versions. They are typically much less expensive than brand-name options.

While moderate alcohol consumption (1-2 drinks) is generally considered safe with these medications, excessive alcohol can reduce their effectiveness and increase the risk of side effects like dizziness and low blood pressure. Alcohol can also make it more difficult to achieve an erection. It's best to limit alcohol intake when using these medications.

If one medication doesn't work, don't give up. Your doctor may: 1) Adjust your dosage, 2) Try the other medication (some men respond better to one than the other), 3) Review other medications you're taking for interactions, 4) Investigate underlying health conditions, or 5) Recommend alternative treatments. It may take several attempts to find the right solution.

No. These medications are not safe for everyone. You should NOT take them if you: use nitrates for chest pain, take riociguat for pulmonary hypertension, have been advised against sexual activity, or are allergic to the medication. You should consult your doctor if you have heart problems, high or low blood pressure, liver or kidney disease, or certain other medical conditions.

You need a prescription from a licensed healthcare provider. Options include: 1) Your primary care doctor, 2) A urologist, 3) Telemedicine services (online doctor consultations), or 4) Men's health clinics. The doctor will review your medical history, current medications, and overall health before prescribing.

Tadalafil is available in low doses (2.5mg or 5mg) for daily use, which allows for spontaneous sexual activity without planning. Sildenafil is typically used as-needed only, not for daily use. Daily Tadalafil may be a good option if you have frequent sexual activity or want complete spontaneity.

Be very careful with online pharmacies. Many sell counterfeit medications that can be dangerous. Only use pharmacies that: 1) Require a valid prescription, 2) Are licensed in your country, 3) Have a verifiable physical address, and 4) Are certified by organizations like NABP (National Association of Boards of Pharmacy). Legitimate telemedicine services that connect you with licensed doctors are generally safe.

Insurance coverage varies widely. Some insurance plans cover ED medications, while others don't. Generic versions are more likely to be covered than brand-name versions. Some plans have quantity limits (e.g., 6 pills per month). Check with your insurance provider for specific coverage details. If not covered, discount programs and generic versions can make these medications more affordable.

Some people split higher-dose pills to save money (e.g., splitting a 100mg Sildenafil pill in half for two 50mg doses). However, you should only do this with your doctor's approval. Not all pills are designed to be split, and splitting may affect the medication's effectiveness. Never split extended-release or coated tablets.

Both medications typically begin working within 30-60 minutes. Sildenafil reaches peak effectiveness around 1 hour, while Tadalafil peaks around 2 hours. However, both can work faster or slower depending on factors like whether you've eaten, your metabolism, and individual response. For best results with Sildenafil, take it on an empty stomach.

No. These medications do not increase sexual desire or libido. They only help with the physical aspect of achieving and maintaining an erection when you are already sexually aroused. If you have low sexual desire, talk to your doctor about other potential causes and treatments.

These medications are not approved for use in women. While some studies have explored their use for female sexual dysfunction, they are not FDA-approved for this purpose and should not be used by women without specific medical guidance. There are other treatments available for female sexual dysfunction.

For mild side effects (headache, flushing, indigestion), they often decrease over time as your body adjusts. Over-the-counter pain relievers can help with headaches. However, seek immediate medical attention if you experience: an erection lasting more than 4 hours, sudden vision or hearing loss, chest pain, severe dizziness, or irregular heartbeat.